Challenges and strategies for accessibility research in the Global South: A panel discussion

Over 80% of the 1 billion people with disabilities in the world live in the Global South, yet, most of the research at the intersection of disability and technology published across HCI venues is based in the Global North. With limited published research, and a large range of socio-cultural, practical and environmental differences across the Global South, HCI researchers and practitioners can encounter unexpected challenges when planning and conducting accessibility studies. The aim of this panel is to bring together three experienced academics who have conducted, managed and published impactful HCI research working with people with disabilities in various regions of the Global South from Latin America to East Africa and South Asia. Panelists will give an initial overview of their experiences conducting research with participants who had different disabilities and other relevant stakeholders, dedicating particular attention to the practical aspects commonly involved in research projects

A Genetic-algorithm-based Approach to the Design of DCT Hardware Accelerators

As modern applications demand an unprecedented level of computational resources, traditional computing system design paradigms are no longer adequate to guarantee significant performance enhancement at an affordable cost. Approximate Computing (AxC) has been introduced as a potential candidate to achieve better computational performances by relaxing non-critical functional system specifications. In this article, we propose a systematic and high-abstraction-level approach allowing the automatic generation of near Pareto-optimal approximate configurations for a Discrete Cosine Transform (DCT) hardware accelerator. We obtain the approximate variants by using approximate operations, having configurable approximation degree, rather than full-precise ones. We use a genetic searching algorithm to find the appropriate tuning of the approximation degree, leading to optimal tradeoffs between accuracy and gains. Finally, to evaluate the actual HW gains, we synthesize non-dominated approximate DCT variants for two different target technologies, namely, Field Programmable Gate Arrays (FPGAs) and Application Specific Integrated Circuits (ASICs). Experimental results show that the proposed approach allows performing a meaningful exploration of the design space to find the best tradeoffs in a reasonable time. Indeed, compared to the state-of-the-art work on approximate DCT, the proposed approach allows an 18% average energy improvement while providing at the same time image quality improvement

Opportunities for Supporting Self-efficacy through Orientation & Mobility Training Technologies for Blind and Partially Sighted People

Orientation and mobility (O&M) training provides essential skills and techniques for safe and independent mobility for blind and partially sighted (BPS) people. The demand for O&M training is increasing as the number of people living with vision impairment increases. Despite the growing portfolio of HCI research on assistive technologies (AT), few studies have examined the experiences of BPS people during O&M training, including the use of technology to aid O&M training. To address this gap, we conducted semi-structured interviews with 20 BPS people and 8 Mobility and Orientation Trainers (MOT). The interviews were thematically analysed and organised into four overarching themes discussing factors influencing the self-efficacy belief of BPS people: Tools and Strategies for O&M training, Technology Use in O&M Training, Changing Personal and Social Circumstances, and Social Influences. We further highlight opportunities for combinations of multimodal technologies to increase access to and effectiveness of O&M training

Mobile Phones as Assistive Technologies: Gaps and Opportunities

In the last decade, mobile phones have become invaluable allays in the everyday lives of people with disabilities. Even in low and middle income countries mobile phones are highly popular and the penetration rate of mobile technology is almost three times higher than for desktop computers and broadband lines. Despite their diffusion and their importance, large datasets on how people with disabilities in lower resourced settings use mobile phones, the services they access and the barriers they encounter when interacting with mobile technology, are scarce. This article presents data from a survey with 1000 participants that explored how people with disabilities use mobile phones and the impact that mobile technology has on their daily lives. Findings highlight the presence of a mobile gap with many people with disability struggling to acquire and operate mobile phones independently. Most respondents had only access to basic or feature phones that lacked appropriate accessibility features and offered limited functionality. However, participants still described mobile phones as invaluable tools that could increase access to basic services and offer support in many important activities in their daily lives

Socioeconomic Status and the Course of Quality of Life in Older Patients with Coronary Heart Disease

BACKGROUND: Previous research suggests that socioeconomic status (SES) might be related to the course of quality of life (QoL) in coronary heart disease (CHD) patients. The authors sought to determine whether there are differences in the course of QoL before and after the incidence of CHD among older persons of differing SES. METHOD: Two hundred two CHD patients were followed up longitudinally using a community-based survey. Data on patients' QoL were collected before the diagnosis and at three follow-up assessments. RESULTS: High SES patients reported better outcomes at the premorbid assessment with fewer depressive feelings and better physical functioning. In physical functioning, similar results were repeated 6 and 12 months after the diagnosis. Additionally, high SES patients showed better role and social functioning 1 year after CHD. A multivariate analysis of variance revealed differential longitudinal pathways in relation to SES in role, social, and physical functioning. CONCLUSION: CHD modulates premorbid differences in depressive feelings. Conversely, high SES leads to better outcomes in all functional domains in the long-term after diagnosis. Postmorbid differences in physical functioning are not directly related to CHD, but rather the reestablishment of a premorbid situation. In contrast, socioeconomic inequalities in social and role functioning are a direct response to the impact of the disease

Amiodarone-induced rosacea

Amiodarone is an anti-arrhythmic agent. Its most common cutaneous side effects are photosensitivity and hyperpigmentation. Furthermore, amiodarone rarely causes allergic rash, exfoliative dermatitis, toxic epidermal necrolysis, leucocytoclastic vasculitis, pseudoporphyria, linear IgA bullous dermatosis, vegetating iododerma and myxoedema. An increased susceptibility to the development of basal cell carcinomas was also reported. Only one case of rosacea due to amiodarone was reported so far. We describe a case of papulo-pustular rosacea which appeared four months after the beginning of the therapy with amiodarone. The disease did not improve despite several topical and oral therapies. However, it improved within six weeks after amiodarone discontinuation and completely cleared up within three months. Follow-up at one year was negative

Prevenzione delle recidive nel paziente precedentemente trattato con isotretinoina orale

Gli autori presentano la loro esperienza relativa alla prevenzione delle recidive nel paziente acneico precedentemente trattato con isotretinoina orale. In particolare, gli autori dimostrano che, alla fine della terapia con isotretinoina orale, l'utilizzodi un retinoide topico (adapalene allo 0,1% o isotretinoina allo 0,05% o tretinoina allo 0,05%), per un periodo continuativo di 6-8 mesi, limita, in modo statisticamente significativo, la comparsa delle recidive

A modified vimentin histological score helps recognize pulmonary sarcomatoid carcinoma in small biopsy samples

Background: As pulmonary sarcomatoid carcinomas (PSCs) are life-threatening tumors, an improvement in their recognition in small-sized tumor samples is clinically warranted. Materials and Methods: Preoperative biopsy samples and paired surgical specimens from 20 pleomorphic carcinomas, two pulmonary blastomas and one carcinosarcoma (training set) were studied for vimentin immunohistochemistry. A modified vimentin histologic score (M-VHS) was devised by multiplying three independently assessed parameters, i.e. the percentage of positive cells (from 0 to 5+, by quintiles), the intensity of immunostaining (low=1 vs. strong=2) and the distribution pattern within the cytoplasm (partial=1 vs. diffuse=2), so ranging from 0 to 20. Forty-eight consecutive and independent cases of non-small cell lung carcinoma (NSCLC), including two additional cases of PSC, were used as control groups (validation set). Results: No differences in M-VHS were found between biopsies and surgical specimens of PSC, thus confirming the occurrence of stable epithelial mesenchymal transition (EMT) and hence the specific diagnosis of PSC. All types of PSC shared the same M-VHS. The M-VHS of 46 conventional NSCLC was by far lower (p<0.0001), whereas two additional cases of PSC showed the same results as the training set. Poorly differentiated NSCLC with marked pleomorphism but not stable EMT did not exhibit significantly increased M-VHS values. Conclusion: M-VHS helped in morphological analysis to render more definite diagnoses on small biopsies of PSC